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Pyridoxamine dihydrochloride

CAS No. 524-36-7

Pyridoxamine dihydrochloride ( Pyridorin | Pyridoxylamine Dihydrochloride )

产品货号. M19616 CAS No. 524-36-7

Pyridoxamine DiHClide 是一种维生素 B6 的盐酸盐。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥340 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Pyridoxamine dihydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Pyridoxamine DiHClide 是一种维生素 B6 的盐酸盐。
  • 产品描述
    Pyridoxamine Dihydrochloride is a hydrochloride salt of one form of vitamin B6.(In Vitro):Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.(In Vivo):Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
  • 体外实验
    Pyridoxylamine (PM), a member of the B6 vitamer family, is a potent scavenger of reactive carbonyls, inhibiting the late stages of glycation reactions that lead to AGE formation.
  • 体内实验
    Pyridoxylamine limits the formation of CML and CEL and cross-linking in skin collagen and, ultimately inhibits the development of nephropathy in STZ-diabetic rats. Pyridoxylamine does not appear to function as an antioxidant since it does not prevent lipid peroxidation reactions. At the same time, it does prevent protein modification by products of lipid peroxidation, including inhibiting formation of malondialdehyde and 4-hydroxynonenal adducts on protein in Zucker rats in vivo.
  • 同义词
    Pyridorin | Pyridoxylamine Dihydrochloride
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Neurological Disease
  • 适应症
    Schizophrenia

化学信息

  • CAS Number
    524-36-7
  • 分子量
    241.12
  • 分子式
    C8H14Cl2N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    Cl.Cl.Cc1ncc(CO)c(CN)c1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Adrover M et al. The pyridoxamine action on Amadori compounds: A reexamination of its scavenging capacity and chelating effect. Bioorg Med Chem. 2008 May 15;16(10):5557-69.
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